Abstract:
In this present investigation, we have extracted and characterized the Tapra fish
oil as well as applied it to evaluate anti-obesity potentiality. The Tapra fish oil had
1.14 ± 0.10 mg KOH/g of acid value, 129.8 ± 5.09 mg KOH/g of saponification
number, 2.67 ± 0.67 mEq/kg of peroxide value, 121.9 ± 2.14 mg of iodine value,
and 17.67 ± 1.45 totox value. Gas Chromatography-Mass Spectrometric analysis
clearly revealed the presence of nine different fatty acids. When the fish oil was
applied to high-fat diet-induced obese mice, it showed significant reduction of body
weight, Body Mass Index, and serum lipid profiles compared to the high-fat dietinduced
obese mice. The levels of leptin and TNF-α were moderately reduced in fish
oil treated high-fat diet-induced obese mice than control obese mice. In conclusion,
the Tapra fish oil was enriched with essential fatty acids and it could be used as an
antiobese food supplement.